human TMEM165 shRNA silencing AAV

Cat. No: shAAV-225780

Availability: 4-5 weeks

Name: AAV-h-TMEM165-shRNA

This is an AAV expressing shRNA for silencing of Human TMEM165.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMEM165
Gene Name: transmembrane protein 165
Gene ID: 55858
Gene Synonyms: CDG2K; FT27; GDT1; TMPT27; TPARL
ORF Size: 975 bp
RefSeq#: NM_018475
Gene Description: TMEM165 encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.479766
HGNC ID: HGNC:30760