human TBPL1 shRNA silencing AAV

Cat. No: shAAV-225141

Availability: 4-5 weeks

Name: AAV-h-TBPL1-shRNA

This is an AAV expressing shRNA for silencing of Human TBPL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TBPL1
Gene Name: TATA-box binding protein like 1
Gene ID: 9519
Gene Synonyms: MGC:8389; MGC:9620; STUD; TLF; TLP; TRF2
ORF Size: 561 bp
RefSeq#: NM_004865
Gene Description: TBPL1 encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. TBPL1 plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
UniGene ID: Hs.486507
HGNC ID: HGNC:11589