human SUFU shRNA silencing AAV

Cat. No: shAAV-224700

Availability: 4-5 weeks

Name: AAV-h-SUFU-shRNA

This is an AAV expressing shRNA for silencing of Human SUFU.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SUFU
Gene Name: SUFU negative regulator of hedgehog signaling
Gene ID: 51684
Gene Synonyms: PRO1280; SUFUH; SUFUXL
ORF Size: 1455 bp
RefSeq#: NM_016169
Gene Description: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.404089
HGNC ID: HGNC:16466