human SGCD shRNA silencing AAV

Cat. No: shAAV-222842

Availability: 4-5 weeks

Name: AAV-h-SGCD-shRNA

This is an AAV expressing shRNA for silencing of Human SGCD.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SGCD
Gene Name: sarcoglycan delta
Gene ID: 6444
Gene Synonyms: 35DAG; CMD1L; DAGD; SG-delta; SGCDP; SGD
ORF Size: 873 bp
RefSeq#: NM_000337
Gene Description: SGCD is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
UniGene ID: Hs.644733
HGNC ID: HGNC:10807