human ROD1 shRNA silencing AAV

Name 
AAV-h-ROD1-shRNA
Cat No 
shAAV-221477
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PTBP3.

shAAV-221477
AAV-h-ROD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTBP3 (polypyrimidine tract binding protein 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
fission yeast differentiation regulator; polypyrimidine tract-binding protein 3; regulator of differentiation 1; ROD1; ROD1 regulator of differentiation 1
Description (eCommerce)
The protein encoded by the PTBP3 gene, polypyrimidine tract-binding protein 3, binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro [taken from NCBI Entrez Gene (Gene ID: 9991)].
Description (Vector)
PTBP3 binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
9991
Gene Name (eCommerce)
polypyrimidine tract binding protein 3
Gene Name (Vector)
polypyrimidine tract binding protein 3
Gene Symbol
PTBP3
HGNC ID
HGNC:10253
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1677
ORF Size (bp)
1677 bp
Protein Name (eCommerce)
Polypyrimidine tract-binding protein 3
RefSeq ID
NM_005156
RefSeq Synonyms
NM_005156, NM_001244898, NM_001244897, NM_001244896, NM_001163790, NM_001163788, BC044585,
Research Areas
mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
The protein encoded by the PTBP3 gene, polypyrimidine tract-binding protein 3, binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro [taken from NCBI Entrez Gene (Gene ID: 9991)].
UniGene ID
Hs.269988
UniProt ID (eCommerce)
O95758

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.