human PMM1 shRNA silencing AAV

Cat. No: shAAV-219270

Availability: 4-5 weeks

Name: AAV-h-PMM1-shRNA

This is an AAV expressing shRNA for silencing of Human PMM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PMM1
Gene Name: phosphomannomutase 1
Gene ID: 5372
Gene Synonyms: Sec53
ORF Size: 789 bp
RefSeq#: NM_002676
Gene Description: Phosphomannomutase catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose, which is essential for N-linked glycosylation and thus the secretion of several glycoproteins as well as for the synthesis of glycosyl-phosphatidyl-inositol (GPI) anchored proteins.
UniGene ID: Hs.75835
HGNC ID: HGNC:9114