human PLA2G15 shRNA silencing AAV

Cat. No: shAAV-219060

Availability: 4-5 weeks

Name: AAV-h-PLA2G15-shRNA

This is an AAV expressing shRNA for silencing of Human PLA2G15.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PLA2G15
Gene Name: phospholipase A2 group XV
Gene ID: 23659
Gene Synonyms: ACS; GXVPLA2; LLPL; LPLA2; LYPLA3
ORF Size: 1239 bp
RefSeq#: NM_012320
Gene Description: Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
UniGene ID: Hs.632199
HGNC ID: HGNC:17163