human PBRM1 shRNA silencing AAV

Cat. No: shAAV-218290

Availability: 4-5 weeks

Name: AAV-h-PBRM1-shRNA

This is an AAV expressing shRNA for silencing of Human PBRM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PBRM1
Gene Name: polybromo 1
Gene ID: 55193
Gene Synonyms: BAF180; PB1
ORF Size: 4959 bp
RefSeq#: NM_018165
Gene Description: This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma.
UniGene ID: Hs.476320
HGNC ID: HGNC:30064