human ID2 shRNA silencing AAV

Cat. No: shAAV-211763

Availability: 4-5 weeks

Name: AAV-h-ID2-shRNA

This is an AAV expressing shRNA for silencing of Human ID2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ID2
Gene Name: inhibitor of DNA binding 2, HLH protein
Gene ID: 3398
Gene Synonyms: bHLHb26; GIG8; ID2A; ID2H
ORF Size: 405 bp
RefSeq#: NM_002166
Gene Description: ID2 belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3.
UniGene ID: Hs.180919
HGNC ID: HGNC:5361