human GTF2I shRNA silencing AAV

Cat. No: shAAV-210649

Availability: 4-5 weeks

Name: AAV-h-GTF2I-shRNA

This is an AAV expressing shRNA for silencing of Human GTF2I.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GTF2I
Gene Name: general transcription factor IIi
Gene ID: 2969
Gene Synonyms: BAP135; BTKAP1; DIWS; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
ORF Size: 2931 bp
RefSeq#: NM_001518
Gene Description: GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
UniGene ID: Hs.647041
HGNC ID: HGNC:4659