human GNPDA2 shRNA silencing AAV

Cat. No: shAAV-210136

Availability: 4-5 weeks

Name: AAV-h-GNPDA2-shRNA

This is an AAV expressing shRNA for silencing of Human GNPDA2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GNPDA2
Gene Name: glucosamine-6-phosphate deaminase 2
Gene ID: 132789
Gene Synonyms: GNP2; SB52
ORF Size: 828 bp
RefSeq#: NM_138335
Gene Description: GNPDA2 is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
UniGene ID: Hs.21398
HGNC ID: HGNC:21526