human GBA2 shRNA silencing AAV

Cat. No: shAAV-209701

Availability: 4-5 weeks

Name: AAV-h-GBA2-shRNA

This is an AAV expressing shRNA for silencing of Human GBA2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GBA2
Gene Name: glucosylceramidase beta 2
Gene ID: 57704
Gene Synonyms: AD035; NLGase; SPG46
ORF Size: 2784 bp
RefSeq#: NM_020944
Gene Description: GBA2 encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.
UniGene ID: Hs.443134
HGNC ID: HGNC:18986