human GALNT7 shRNA silencing AAV

Cat. No: shAAV-209602

Availability: 4-5 weeks

Name: AAV-h-GALNT7-shRNA

This is an AAV expressing shRNA for silencing of Human GALNT7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GALNT7
Gene Name: polypeptide N-acetylgalactosaminyltransferase 7
Gene ID: 51809
Gene Synonyms: GALNAC-T7; GalNAcT7
ORF Size: 1974 bp
RefSeq#: NM_017423
Gene Description: GALNT7 encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.
UniGene ID: Hs.548088
HGNC ID: HGNC:4129