human FLT3LG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FLT3LG.
shAAV-209164
AAV-h-FLT3LG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FLT3LG (fms related tyrosine kinase 3 ligand). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FL; FLT3L
Description (Vector)
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 (PubMed 20933441)).(supplied by OMIM, Jan 2011)
Gene ID
2323
Gene Name (Vector)
fms related tyrosine kinase 3 ligand
Gene Symbol
FLT3LG
HGNC ID
HGNC:3766
ORF Size (aa)
462
RefSeq ID
NM_001459
RefSeq Synonyms
NM_001459, NM_001278638, NM_001278637, NM_001204503, NM_001204502, BC144129, BC136464, BC126293, BC028001,
Species
human
UniGene ID
Hs.428
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.