human EXO1 shRNA silencing AAV

Cat. No: shAAV-208172

Availability: 4-5 weeks

Name: AAV-h-EXO1-shRNA

This is an AAV expressing shRNA for silencing of Human EXO1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EXO1
Gene Name: exonuclease 1
Gene ID: 9156
Gene Synonyms: HEX1; hExoI
ORF Size: 2541 bp
RefSeq#: NM_130398
Gene Description: EXO1 encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
UniGene ID: Hs.498248
HGNC ID: HGNC:3511