human DUSP14 shRNA silencing AAV

Cat. No: shAAV-207413

Availability: 4-5 weeks

Name: AAV-h-DUSP14-shRNA

This is an AAV expressing shRNA for silencing of Human DUSP14.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DUSP14
Gene Name: dual specificity phosphatase 14
Gene ID: 11072
Gene Synonyms: MKP-L; MKP6
ORF Size: 597 bp
RefSeq#: NM_007026
Gene Description: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 (PubMed 19228121)).(supplied by OMIM, Dec 2009)
UniGene ID: Hs.91448
HGNC ID: HGNC:17007