human CPSF6 shRNA silencing AAV

Cat. No: shAAV-205935

Availability: 4-5 weeks

Name: AAV-h-CPSF6-shRNA

This is an AAV expressing shRNA for silencing of Human CPSF6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CPSF6
Gene Name: cleavage and polyadenylation specific factor 6
Gene ID: 11052
Gene Synonyms: CFIM; CFIM68; HPBRII-4; HPBRII-7
ORF Size: 1767 bp
RefSeq#: NM_007007
Gene Description: CPSF6 is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
UniGene ID: Hs.369606
HGNC ID: HGNC:13871