human CCT4 shRNA silencing AAV

Cat. No: shAAV-204559

Availability: 4-5 weeks

Name: AAV-h-CCT4-shRNA

This is an AAV expressing shRNA for silencing of Human CCT4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CCT4
Gene Name: chaperonin containing TCP1 subunit 4
Gene ID: 10575
Gene Synonyms: CCT-DELTA; Cctd; SRB
ORF Size: 1620 bp
RefSeq#: NM_006430
Gene Description: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 (PubMed 9819444)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.421509
HGNC ID: HGNC:1617