human CARD10 shRNA silencing AAV

Cat. No: shAAV-204079

Availability: 4-5 weeks

Name: AAV-h-CARD10-shRNA

This is an AAV expressing shRNA for silencing of Human CARD10.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CARD10
Gene Name: caspase recruitment domain family member 10
Gene ID: 29775
Gene Synonyms: BIMP1; CARMA3
ORF Size: 3093 bp
RefSeq#: NM_014550
Gene Description: The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 (PubMed 11259443)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.57973
HGNC ID: HGNC:16422