human CARD10 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CARD10.
shAAV-204079
AAV-h-CARD10-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CARD10 (caspase recruitment domain family member 10). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BIMP1; CARMA3
Description (Vector)
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 (PubMed 11259443)).(supplied by OMIM, Mar 2008)
Gene ID
29775
Gene Name (Vector)
caspase recruitment domain family member 10
Gene Symbol
CARD10
HGNC ID
HGNC:16422
ORF Size (aa)
3093
ORF Size (bp)
3093 bp
RefSeq ID
NM_014550
RefSeq Synonyms
NM_014550, BC117403, BC113659,
Species
human
UniGene ID
Hs.57973
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.