human ATP8B1 shRNA silencing AAV

Cat. No: shAAV-201787

Availability: 4-5 weeks

Name: AAV-h-ATP8B1-shRNA

This is an AAV expressing shRNA for silencing of Human ATP8B1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP8B1
Gene Name: ATPase phospholipid transporting 8B1
Gene ID: 5205
Gene Synonyms: ATPIC; BRIC; FIC1; ICP1; PFIC; PFIC1
ORF Size: 3753 bp
RefSeq#: NM_005603
Gene Description: ATP8B1 encodes a member of the P-type cation transport ATPase family, which belongs to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. Mutations in this gene may result in progressive familial intrahepatic cholestasis type 1 and in benign recurrent intrahepatic cholestasis.
UniGene ID: Hs.216623
HGNC ID: HGNC:3706