human ACSL4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-200251
Availability:
4-5 weeks
Name:
AAV-h-ACSL4-shRNA
This is an AAV expressing shRNA for silencing of Human ACSL4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ACSL4
- Gene Name
- acyl-CoA synthetase long-chain family member 4
- Gene ID
- 2182
- Gene Synonyms
- ACS4; FACL4; LACS4; MRX63; MRX68
- ORF Size
- 2013 bp
- RefSeq#
- NM_004458
- Gene Description
- ACSL4 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
- UniGene ID
- Hs.268785
- HGNC ID
- HGNC:3571
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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