human PPP1R9A shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PPP1R9A

Gene Name

protein phosphatase 1 regulatory subunit 9A

Gene ID

55607

Gene Synonyms

Neurabin-I; NRB1; NRBI

ORF Size

3273 bp

RefSeq#

NM_017650

Gene Description

PPP1R9A is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. PPP1R9A is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.21816

HGNC ID

HGNC:14946