rat SIAT7F shRNA silencing AAV

Cat. No: shAAV-293479

Availability: 4-5 weeks

Name: AAV-r-SIAT7F-shRNA

This is an AAV expressing shRNA for silencing of Rat St6galnac6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: St6galnac6
Gene Name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Gene ID: 407765
Gene Synonyms: Siat7F
ORF Size: 600 bp
RefSeq#: NM_001015036
Gene Description: Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)), a representative tumor-associated antigen in cancers of the pancreas and colon, in colon tissues.