rat DOK1 shRNA silencing AAV

Cat. No: shAAV-294027

Availability: 4-5 weeks

Name: AAV-r-DOK1-shRNA

This is an AAV expressing shRNA for silencing of Rat Dok1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Dok1
Gene Name: docking protein 1
Gene ID: 312477
Gene Synonyms: Dok-1
ORF Size: 1443 bp
RefSeq#: NM_001025416
Gene Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.