rat HNRPDL shRNA silencing AAV

Cat. No: shAAV-294710

Availability: 4-5 weeks

Name: AAV-r-HNRPDL-shRNA

This is an AAV expressing shRNA for silencing of Rat Hnrnpdl.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Hnrnpdl
Gene Name: heterogeneous nuclear ribonucleoprotein D-like
Gene ID: 305178
Gene Synonyms: hnRNP DL; Hnrpdl
ORF Size: 969 bp
RefSeq#: NM_001033696
Gene Description: Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence.