mouse HLTF shRNA silencing AAV

Cat. No: shAAV-261433

Availability: 4-5 weeks

Name: AAV-m-HLTF-shRNA

This is an AAV expressing shRNA for silencing of Mouse HLTF.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: HLTF
Gene Name: helicase-like transcription factor
Gene ID: 20585
Gene Synonyms: AF010600; BC057116; P113; Smarca3; Snf2l3;
ORF Size: 3012 bp
RefSeq#: NM_009210
Gene Description: Has both helicasee and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
UniGene ID: Mm.209650