mouse RHOU shRNA silencing AAV

Cat. No: shAAV-270553

Availability: 4-5 weeks

Name: AAV-m-RHOU-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rhou.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rhou
Gene Name: ras homolog family member U
Gene ID: 69581
Gene Synonyms: 2310026M05Rik; AI182090; Arhu; CDC42L1; G28K; mG28K; WRCH-1; WRCH1
ORF Size: 783 bp
RefSeq#: NM_133955
Gene Description: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
UniGene ID: Mm.168257