human ITPKB shRNA silencing AAV

Cat. No: shAAV-212547

Availability: 4-5 weeks

Name: AAV-h-ITPKB-shRNA

This is an AAV expressing shRNA for silencing of Human ITPKB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ITPKB
Gene Name: inositol-trisphosphate 3-kinase B
Gene ID: 3707
Gene Synonyms: IP3-3KB; IP3K; IP3K-B; IP3KB; PIG37
ORF Size: 1935 bp
RefSeq#: NM_002221
Gene Description: The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
UniGene ID: Hs.659396
HGNC ID: HGNC:6179