human CHCHD4 shRNA silencing AAV

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

CHCHD4

Gene Name

coiled-coil-helix-coiled-coil-helix domain containing 4

Gene ID

131474

Gene Synonyms

MIA40; TIMM40

ORF Size

429 bp

RefSeq#

NM_144636

Gene Description

CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX(9)C-CX(9)C- motif in the C terminus (Hofmann et al., 2005 (PubMed 16185709)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.517815

HGNC ID

HGNC:26467