mouse PHF21A shRNA silencing AAV

Cat. No: shAAV-268535

Availability: 4-5 weeks

Name: AAV-m-PHF21A-shRNA

This is an AAV expressing shRNA for silencing of Mouse Phf21a.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Phf21a
Gene Name: PHD finger protein 21A
Gene ID: 192285
Gene Synonyms: 80kDa; Bhc; Bhc80; D030065N23Rik; PFTF1
ORF Size: 1671 bp
RefSeq#: NM_138755
Gene Description: Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation.
UniGene ID: Mm.450689