human EED shRNA silencing AAV

Cat. No: shAAV-207573

Availability: 4-5 weeks

Name: AAV-h-EED-shRNA

This is an AAV expressing shRNA for silencing of Human EED.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EED
Gene Name: embryonic ectoderm development
Gene ID: 8726
Gene Synonyms: HEED; WAIT1
ORF Size: 1401 bp
RefSeq#: NM_003797
Gene Description: EED encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
UniGene ID: Hs.503510
HGNC ID: HGNC:3188