human HPRT1 shRNA silencing AAV

Cat. No: shAAV-211501

Availability: 4-5 weeks

Name: AAV-h-HPRT1-shRNA

This is an AAV expressing shRNA for silencing of Human HPRT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HPRT1
Gene Name: hypoxanthine phosphoribosyltransferase 1
Gene ID: 3251
Gene Synonyms: HGPRT; HPRT
ORF Size: 657 bp
RefSeq#: NM_000194
Gene Description: HPRT1 is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
UniGene ID: Hs.412707
HGNC ID: HGNC:5157