mouse PCNA shRNA silencing AAV

Cat. No: shAAV-268230

Availability: 4-5 weeks

Name: AAV-m-PCNA-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pcna.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pcna
Gene Name: proliferating cell nuclear antigen
Gene ID: 18538
ORF Size: 786 bp
RefSeq#: NM_011045
Gene Description: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
UniGene ID: Mm.7141