mouse ADH7 shRNA silencing AAV

Cat. No: shAAV-252143

Availability: 4-5 weeks

Name: AAV-m-ADH7-shRNA

This is an AAV expressing shRNA for silencing of Mouse Adh7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Adh7
Gene Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Gene ID: 11529
Gene Synonyms: Adh-3; Adh-3e; Adh-3t; Adh3; Adh3-e; Adh3-t; Adh4; Adt-1; AI325182
ORF Size: 1125 bp
RefSeq#: NM_009626
Gene Description: Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
UniGene ID: Mm.8473