human PDGFRA shRNA silencing AAV

Cat. No: shAAV-218508

Availability: 4-5 weeks

Name: AAV-h-PDGFRA-shRNA

This is an AAV expressing shRNA for silencing of Human PDGFRA.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDGFRA
Gene Name: platelet derived growth factor receptor alpha
Gene ID: 5156
Gene Synonyms: CD140A; GAS9; PDGFR-2; PDGFR2; RHEPDGFRA
ORF Size: 2232 bp
RefSeq#: NM_006206
Gene Description: PDGFRA encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
UniGene ID: Hs.74615
HGNC ID: HGNC:8803