human TBCE shRNA silencing AAV

Cat. No: shAAV-225122

Availability: 4-5 weeks

Name: AAV-h-TBCE-shRNA

This is an AAV expressing shRNA for silencing of Human TBCE.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TBCE
Gene Name: tubulin folding cofactor E
Gene ID: 6905
Gene Synonyms: HRD; KCS; KCS1; pac2
ORF Size: 1584 bp
RefSeq#: NM_003193
Gene Description: Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.498143
HGNC ID: HGNC:11582