human KLF11 shRNA silencing AAV

Cat. No: shAAV-213175

Availability: 4-5 weeks

Name: AAV-h-KLF11-shRNA

This is an AAV expressing shRNA for silencing of Human KLF11.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KLF11
Gene Name: Kruppel like factor 11
Gene ID: 8462
Gene Synonyms: FKLF; FKLF1; MODY7; TIEG2; Tieg3
ORF Size: 1539 bp
RefSeq#: NM_003597
Gene Description: KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.12229
HGNC ID: HGNC:11811