human SAPS3 shRNA silencing AAV

Cat. No: shAAV-222247

Availability: 4-5 weeks

Name: AAV-h-SAPS3-shRNA

This is an AAV expressing shRNA for silencing of Human PPP6R3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPP6R3
Gene Name: protein phosphatase 6 regulatory subunit 3
Gene ID: 55291
Gene Synonyms: C11orf23; PP6R3; SAP190; SAPL; SAPLa; SAPS3
ORF Size: 2535 bp
RefSeq#: NM_018312
Gene Description: Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 (PubMed 16769727)).(supplied by OMIM, Nov 2010)
UniGene ID: Hs.503022
HGNC ID: HGNC:1173