human ARL2BP shRNA silencing AAV

Cat. No: shAAV-201404

Availability: 4-5 weeks

Name: AAV-h-ARL2BP-shRNA

This is an AAV expressing shRNA for silencing of Human ARL2BP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARL2BP
Gene Name: ADP ribosylation factor like GTPase 2 binding protein
Gene ID: 23568
Gene Synonyms: BART; BART1; RP66
ORF Size: 459 bp
RefSeq#: NM_012106
Gene Description: ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.
UniGene ID: Hs.645184
HGNC ID: HGNC:17146