mouse GFM2 shRNA silencing AAV

Cat. No: shAAV-278853

Availability: 4-5 weeks

Name: AAV-m-GFM2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Gfm2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Gfm2
Gene Name: G elongation factor, mitochondrial 2
Gene ID: 320806
Gene Synonyms: 6530419G12Rik; A930009M04Rik; EF-G2mt; EFG2; MST027; RRF2mt
ORF Size: 2334 bp
RefSeq#: NM_177266
Gene Description: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
UniGene ID: Mm.219675