mouse PAPSS1 shRNA silencing AAV

Cat. No: shAAV-268050

Availability: 4-5 weeks

Name: AAV-m-PAPSS1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Papss1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Papss1
Gene Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 1
Gene ID: 23971
Gene Synonyms: AI325286; Asapk; SK1
ORF Size: 1812 bp
RefSeq#: NM_011863
Gene Description: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
UniGene ID: Mm.244912