human CRBN shRNA silencing AAV

Cat. No: shAAV-205967

Availability: 4-5 weeks

Name: AAV-h-CRBN-shRNA

This is an AAV expressing shRNA for silencing of Human CRBN.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CRBN
Gene Name: cereblon
Gene ID: 51185
Gene Synonyms: MRT2; MRT2A
ORF Size: 1329 bp
RefSeq#: NM_016302
Gene Description: CRBN encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.18925
HGNC ID: HGNC:30185