mouse MARK3 shRNA silencing AAV

Cat. No: shAAV-264272

Availability: 4-5 weeks

Name: AAV-m-MARK3-shRNA

This is an AAV expressing shRNA for silencing of Mouse Mark3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Mark3
Gene Name: MAP/microtubule affinity regulating kinase 3
Gene ID: 17169
Gene Synonyms: 1600015G02Rik; A430080F22Rik; C-TAK1; Emk2; ETK-1; ETK1; MPK10
ORF Size: 1287 bp
RefSeq#: NM_022801
Gene Description: Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.
UniGene ID: Mm.425769