human DAK shRNA silencing AAV

Cat. No: shAAV-206579

Availability: 4-5 weeks

Name: AAV-h-DAK-shRNA

This is an AAV expressing shRNA for silencing of Human TKFC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TKFC
Gene Name: triokinase and FMN cyclase
Gene ID: 26007
Gene Synonyms: DAK; NET45
ORF Size: 1728 bp
RefSeq#: NM_015533
Gene Description: DAK is a member of the family of dihydroxyacetone kinases, which have a protein structure distinct from other kinases. The product of this gene phosphorylates dihydroxyacetone, and also catalyzes the formation of riboflavin 4',5'-phosphate (aka cyclin FMN) from FAD. Several alternatively spliced transcript variants have been identified, but the full-length nature of only one has been determined.
UniGene ID: Hs.6278
HGNC ID: HGNC:24552