human PARP4 shRNA silencing AAV

Cat. No: shAAV-218244

Availability: 4-5 weeks

Name: AAV-h-PARP4-shRNA

This is an AAV expressing shRNA for silencing of Human PARP4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PARP4
Gene Name: poly(ADP-ribose) polymerase family member 4
Gene ID: 143
Gene Synonyms: ADPRTL1; ARTD4; p193; PARP-4; PARPL; PH5P; VAULT3; VPARP; VWA5C
ORF Size: 5175 bp
RefSeq#: NM_006437
Gene Description: PARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.
UniGene ID: Hs.718412
HGNC ID: HGNC:271

Product	Cat No.
Ad-h-PARP4	ADV-218244
Ad-h-PARP4-shRNA	shADV-218244