mouse PIKFYVE shRNA silencing AAV

Cat. No: shAAV-268659

Availability: 4-5 weeks

Name: AAV-m-PIKFYVE-shRNA

This is an AAV expressing shRNA for silencing of Mouse Pikfyve.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Pikfyve
Gene Name: phosphoinositide kinase, FYVE finger containing
Gene ID: 18711
Gene Synonyms: 5230400C17Rik; p235; Pip5k; Pip5k3; Pipk5k3; PipkIII
ORF Size: 6156 bp
RefSeq#: NM_011086
Gene Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
UniGene ID: Mm.38370