human EIF2B1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF2B1

Gene Name

eukaryotic translation initiation factor 2B subunit alpha

Gene ID

1967

Gene Synonyms

EIF2B; EIF2BA

ORF Size

918 bp

RefSeq#

NM_001414

Gene Description

EIF2B1 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

UniGene ID

Hs.716475

HGNC ID

HGNC:3257