human GMPPB shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GMPPB

Gene Name

GDP-mannose pyrophosphorylase B

Gene ID

29925

Gene Synonyms

MDDGA14; MDDGB14; MDDGC14

ORF Size

1083 bp

RefSeq#

NM_013334

Gene Description

GMPPB is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.

UniGene ID

Hs.567488

HGNC ID

HGNC:22932