human ITPKB shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ITPKB

Gene Name

inositol-trisphosphate 3-kinase B

Gene ID

3707

Gene Synonyms

IP3-3KB; IP3K; IP3K-B; IP3KB; PIG37

ORF Size

1935 bp

RefSeq#

NM_002221

Gene Description

The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

UniGene ID

Hs.659396

HGNC ID

HGNC:6179