human SIX6 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SIX6

Gene Name

SIX homeobox 6

Gene ID

4990

Gene Synonyms

MCOPCT2; ODRMD; OPTX2; Six9

ORF Size

741 bp

RefSeq#

NM_007374

Gene Description

SIX6 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

UniGene ID

Hs.194756

HGNC ID

HGNC:10892